An in vitro study of the quality of essential drugs available on the rwandan market

• Acknowledgements
  
  • At the end of this thesis, I would like to express my gratitude to the government of Rwanda (GOR) for the provision of a scholarship to support my studies in Belgium.
    
  • I wish to thank Prof.Dr. J.P. Remon, for accepting me in his laboratory and promoting this work. His encouragement, inspiration and moral support were very important in the accomplishment of this work.
    
• I. Introduction, Background, and Objectives
  
  • I.1 Introduction
    
  • I. 2 Background
    
  • I.3 Objectives
    
• II. Quantitative drug analysis and evaluation of the influence of accelerated stability testing on the in vitro dissolution.
  
  • II.1. Amoxicillin formulations
    
    • II.1.1 Material and equipment
      
    • II.1.2 Quantitative drug analysis
      
    • II.1.3 In vitro dissolution
      
  • II.2 Acetylsalicylic acid formulations
    
    • II.2.1 Material and equipment
      
    • II.2.2 Quantitative drug analysis
      
    • II.2.3 In vitro dissolution
      
    • 2.3.2 Results
      
  • II.3 Sulfamethoxazole / Trimethoprim (Cotrimoxazole) formulations
    
    • II.3.1 Material and equipment
      
    • 3.2.2 Results
      
    • II.3.3 In vitro dissolution
      
  • II.4 Metronidazole formulations
    
    • II.4.1 Material and equipment
      
    • II.4.3 In vitro dissolution
      
    • 4.3.1 Methods
      
    • 4.2.2 Results
      
  • II.5 Paracetamol formulations
    
    • II.5.1 Material and equipment
      
    • II.5.2 Quantitative drug analysis
      
    • 5.2.1 Methods
      
    • 5.2.2 Results
      
    • II.5.3 In vitro dissolution
      
    • 5.3.1 Methods
      
    • 5.3.2 Results
      
  • II.6 Quinine formulations
    
    • II.6.1 Material and equipment
      
    • II.6.2 Quantitative drug analysis
      
    • 6.2.1 Methods
      
    • 6.2.2 Results
      
    • II.6.3. In vitro dissolution
      
    • 6.3.1 Methods
      
    • 6.3.2 Results
      
  • II.7 Sulfadoxine & Pyrimethamine formulations
    
    • II.7.1 Material and equipment
      
    • II.7.2 Quantitative drug analysis
      
    • 7.2.1 Methods
      
    • 7.2.2 Results
      
    • II.7.3 In vitro dissolution
      
    • 7.3.1 Methods
      
• III. Discussion
  
• IV. Conclusion and recommendations
  
• References