Interaction of quinolines and artemisinin based antimalarials drugs with ferriprotoporphyrin IX

• Abstract
  
• Chapter 1 Introduction
  
• Chapter 2 Literature Survey
  
• Hemoglobin
  
• Heme
  
• Small peptides
  
• Hemin
  
• Small peptides
  
  • Plasmepsin I, II and IV (aspartic proteases),HAP
    
  • Peptide transporter
    
• HRP-2
  
• Parasite membrane
  
• Red cell membrane
  
  • Drug uptake through biological membrane by passive diffusion phenomena
    
    • Blood schizontocidal antimalarials
      
  • Serine protease
    
• DIGESTIVE VACUOLE OF PLASMODIA
  
  • 2.3 Mechanisms of resistance of parasite to current drugs
    
• Chapter 3 Experimental materials and methods